Issues in antiemetic therapy

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Antiemetic therapy in patients receiving cancer chemotherapy.

PURPOSE/OBJECTIVES To examine the currently available antiemetic medications and review their uses in the treatment of chemotherapy-induced nausea and vomiting (NV). DATA SOURCES Published articles and book chapters. DATA SYNTHESIS NV is a common yet potentially serious side effect of chemotherapy. Nurses must understand the physiology of NV, its impact on patients, and the proper use of an...

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Multimodal antiemetic therapy and emetic risk profiling.

INTRODUCTION Postoperative nausea and vomiting (PONV) is a common problem with no simple solution. This review highlights factors that are known to increase the risk of PONV. It examines the various data on pharmacological and non-pharmacological methods that have been used to prevent PONV. METHODS Peer-reviewed journals on the subject were covered. CONCLUSION Patient, surgical and anaesthe...

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Stem Cell Therapy: the ethical issues

The ability to culture human stem cells long term, and possibly indefinitely, and to control how such cells specialise to form the different tissues of the body offers the possibility of major advances in healthcare. Stem cells have been isolated and cultured, but a great deal of research is required to develop cell lines which can generate replacement cells and tissues to treat many diseases.S...

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Chemotherapy-induced nausea and vomiting: which antiemetic for which therapy?

Chemotherapy-induced nausea and vomiting (CINV) remains an important and common toxicity of cancer treatment. Recent guideline revisions have classified chemotherapeutic agents into four categories of emesis risk without the use of preventive agents: high (> 90%), moderate (30%--90%), low (10%-30%), and minimal (< 10%). Currently available antiemetic agents, including corticosteroids, 5-hydroxy...

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Efficacy of Olanzapine Combined Therapy for Patients Receiving Highly Emetogenic Chemotherapy Resistant to Standard Antiemetic Therapy

OBJECTIVE Olanzapine is proved to be effective for chemotherapy induced nausea and vomiting (CINV). But its efficacy in combination with standard antiemetic therapy is unknown. The purpose of this study is to prove the preventive effect of olanzapine for the prevention of CINV caused by highly emetogenic chemotherapy when used with standard antiemetic therapy. METHOD Gynecologic cancer patien...

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ژورنال

عنوان ژورنال: Cancer

سال: 1996

ISSN: 0008-543X,1097-0142

DOI: 10.1002/(sici)1097-0142(19960301)77:5<823::aid-cncr3>3.0.co;2-f